At the Shaanxi Science and Technology Awards Conference, the “3D printed movable artificial cervical spine” developed by the team led by Professor He Xijing, the leader of the spinal surgery department of the Second Affiliated Hospital of Xi’an Jiaotong University, won the first prize of Shaanxi Science and Technology.

This is also the first time that Professor He Xijing won the first prize of Shaanxi Province Science and Technology Award for his research results on "Cell protection, functional recovery and treatment of diseases related to spinal cord injury". As the vice chairman of the International Society for Prosthetics and the chairman of the Professional Committee of Prosthetics of the Chinese Medical Doctor Association, Professor Xijing He is a well-deserved "big guy" in the orthopedics field.

3D printing movable artificial cervical spine technology leads the world

Low-key, elegant, and modest are the first impressions left by Professor He Xijing. "If cervical spine lesions compress the spinal cord, such as severe cervical spondylosis, the intervertebral disc must be removed before the operation is performed. The compression of the spinal cord can be relieved. The current practice in the world is to add a titanium cage to the removed part, requiring the doctor to be on the operating table. However, the collapse rate of the hand-cut titanium cage is as high as 79.7%-93.3%, and it is easy to cause internal fixation loosening and displacement, leading to complications such as recurrence of clinical symptoms. In addition, all cervical spine surgery must be fixed and fused , The cervical spine in the surgical part will permanently lose its motor function, which will affect the patient’s quality of life after surgery.” He Xijing described vividly.

To this end, He Xijing led the team to start the research on titanium cage technology. "In the beginning, I experimented with goats, and every time I adjusted, I told the factory engineer what was inappropriate. The engineer would draw the drawing and send it to the workshop for processing. This process usually takes at least three months, and the cycle is indeed too long. During the development process, we saw that 3D technology can print houses and heart stents, so we thought of using 3D technology to directly print titanium cages, so we put them into practice. This idea has brought us to the forefront of the world."

He Xijing led the team combined with metal 3D printing technology to develop a personalized dome titanium cage artificial cervical spine over several years, and innovatively proposed the implantation of a movable artificial vertebral body-intervertebral disc complex after subtotal vertebral body resection. , The concept of reconstructing the function of the vertebral body motor unit, developed a movable artificial cervical prosthesis and an artificial atlanto-tooth joint. So far, the world's first movable artificial atlantoaxial joint replacement operation has been successfully carried out. The technology now has invention patents in China, the European Union and the United States.

This innovative technology can not only be accurate to digital measurement, but also shorten the patient's operation time, but also has less bleeding and improved safety. "We are now planning to do ceramic treatment on the surface of the prosthesis, which is expected to extend the service life of this material to 30 to 40 years." He Xijing said confidently.

A leader in orthopedics

Professor He Xijing went to Switzerland and Australia to study the clinical surgical treatment of scoliosis and spinal diseases, and the theory and technology of artificial joint replacement. He has accumulated rich clinical experience in the treatment of a large number of intractable and high-risk diseases in orthopedics, and has cured many clinical cases. Intractable diseases.

Professor He Xijing cooperated with the University of Hong Kong and the University of Rochester in the experimental research and clinical application of allogeneic olfactory ensheathing cell transplantation in the treatment of spinal cord injury. It has received good clinical effects and improved the quality of life of paraplegic patients. At present, the use of olfactory ensheathing cell transplantation to treat spinal cord injury is the longest follow-up time in the world, which has been more than 10 years. This subject won the first prize of Shaanxi Science and Technology Award in 2013. Professor He said: "In the future, 3D technology will be used to print cells to make biofilms, which will be applied to the injured spinal cord, so that cells can be transplanted without injection."

In 2003, He Xijing took the lead in the treatment of scoliosis with minimally invasive thoracoscopic internal fixation, which is at the leading level in China and filled the gap in the Northwest. The treatment of intervertebral disc herniation under foraminal endoscope has the characteristics of less trauma, less bleeding and quick recovery. He cooperated with Professor Hoogland, the inventor of the German TESSYS technology, to establish a training base for intervertebral endoscope. He Xijing has extensive clinical experience in the treatment of cervical spondylosis, especially good at anterior and posterior upper cervical spine surgery. The development of artificial cervical vertebra joints has won 20 national invention patents and utility model patents, and has won a number of national natural science funds and education Funded by the Ministry of Doctoral Program.

Work hard to build a platform to promote development

This year is the fifth year that Professor He Xijing has served as the chairperson of the Neurorestorative Professional Committee of the Chinese Medical Doctor Association. Through this platform, a team of highly sophisticated experts has been established across the country, creating conditions for the development of neurorestorative medicine in my country. . The Neurorehabilitation Professional Committee of the Chinese Medical Doctor Association has also established some sub-specialties such as spinal cord injury, brain injury, pediatrics, and tissue engineering.

In recent years, the Neural Repair Branch of the Chinese Medical Doctor Association has organized domestic scholars to participate in international neurorestorative academic activities, and introduced internationally renowned neurorestorative experts and scholars into the country for academic exchanges. After four years of development, this team is currently growing. The Neural Repair Professional Committee of the Chinese Medical Doctor Association also conducts joint experiments and multi-center experiments in some hospitals and universities in the United Nations to jointly promote the development of my country's nerve repair industry.

"Now there is a lot of pressure. Our 3D printing technology has already been imitated. If we slow down, someone will be ahead of us. The urgent task now is to transform scientific and technological achievements into clinical applications and produce products. And then to promote it, not only to promote domestically, but more importantly, to occupy the leading position of international independent intellectual property rights." Professor He Xijing said.

As the leader of the National Key Clinical Specialty, Professor He Xijing always emphasized the power of the team during the interview. “I have a very good team, with a group of young professors and doctors, and leaders who fully support our work. The road of technological innovation keeps moving forward."

In this era of innovation and entrepreneurship by the whole people, He Xijing and his team have created the pride of the Chinese people through the technological innovation of movable and fixed spine, and led the development direction of movable and fixed spine in the world.

Link to this article： Research and develop 3D printing movable artificial cervical spine to solve the world's problems

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